Antiestrogens are designed to antagonize hormone induced proliferation and ERalpha target gene expression in mammary tumor cells.Commonly used drugs such as OH-Tamoxifen and ICI 182780 (Fulvestrant) block cell cycle progression in G0/G1.Inversely, the effect of cell cycle stage on ER regulated gene expression has not been tested directly.We show th
Changes in radioactive decay rates due to solar flares have attracted increasing scientific attention in recent decades.In previous studies we demonstrated that solar flares cause changes in the decay rate of 241Am, 222Rn, and 232Th.The change in the count rate of 54Mn due to solar flares, as observed by scholars at Purdue University in 2006, encou
Abstract This observational study catalogues the overlap in Dried Fruits metabolites between matched bronchoalveolar lavage fluid (BALF) and plasma, identifies the degree of congruence between these metabolomes in human and mouse, and determines how molecules may change in response to cigarette smoke (CS) exposure.Matched BALF and plasma was collec